GDAs or glucose disposal agents are growing in popularity within the supplement industry. Essentially what these are made for are to help manage glucose and insulin levels in an effort to increase partitioning into positive compartments. In this series, I want to go over my favorite glucose disposal agent ingredients including chromium, berberine, cinnamon, gymnema, banaba leaf, and alpha lipoic acid.<\/p>\n
First, we\u2019ll begin with chromium. Chromium regulates insulin levels and improves insulin actions within our bodies mainly from its main mechanism that is connected to chromodulin (a protein that changes the signaling of insulin receptors in the body.) Once chromodulin isn’t functioning properly, insulin functioning is drastically reduced. Luckily, chromium has a tremendous amount of literature I would like to go over to ensure you have a full understanding of its benefits and method of action. A study from Abdollahi et al looked at the effect of chromium on glucose and lipid profiles in patients with type 2 diabetes (a meta-analysis review of randomized trials.) The abstract is stated as follows: Chromium (Cr) as an essential trace element in metabolism of carbohydrate, lipid and protein is currently prescribed to control diabetes mellitus (DM). The objective of this meta-analysis was to compare the effect of Cr versus placebo (Pl) on glucose and lipid profiles in patients with type 2 DM. Literature searches in PubMed, Scopus, Scirus, Google Scholar and IranMedex was made by use of related terms during the period of 2000-2012. Eligible studies were randomized clinical trials (RCTs) with intake of Cr higher than 250 \u00b5g at least for three months in type 2 DM. Glycated hemoglobin (HbA1c), fasting blood sugar (FBS), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), very low-density lipoprotein cholesterol (VLDL-C), triglyceride (TG), and body mass index (BMI) were the main outcomes. Seven out of 13 relevant studies met the criteria and were included in the meta-analysis. HbA1c change in diabetic patients in Cr supplement therapy comparing to Pl was -0.33 with 95%CI= -0.72 to 0.06 (P= 0.1). Change of FBG in Cr therapy vs. Pl was -0.95 with 95%CI= -1.42 to -0.49 (P< 0.0001). TC change in Cr therapy vs. Pl was 0.07 with 95%CI= -0.16 to 0.31 (P= 0.54). TG change in diabetic patients in Cr supplement therapy comparing to Pl was -0.15 with 95%CI= -0.36 to 0.07 (P= 0.18). Cr lowers FBS but does not affect HbA1c, lipids and BMI (1.)<\/p>\n
References<\/p>\n
GDAs or glucose disposal agents are growing in popularity within the supplement industry. Essentially what these are made for are to help manage glucose and insulin levels in an effort to increase partitioning into positive compartments. In this series, I want to go over my favorite glucose disposal agent ingredients including chromium, berberine, cinnamon, gymnema, […]<\/p>\n","protected":false},"author":8,"featured_media":3141,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[296,2339,5,1],"tags":[],"_links":{"self":[{"href":"https:\/\/redcon1online.com\/wp-json\/wp\/v2\/posts\/3133"}],"collection":[{"href":"https:\/\/redcon1online.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/redcon1online.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/redcon1online.com\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/redcon1online.com\/wp-json\/wp\/v2\/comments?post=3133"}],"version-history":[{"count":2,"href":"https:\/\/redcon1online.com\/wp-json\/wp\/v2\/posts\/3133\/revisions"}],"predecessor-version":[{"id":3135,"href":"https:\/\/redcon1online.com\/wp-json\/wp\/v2\/posts\/3133\/revisions\/3135"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/redcon1online.com\/wp-json\/wp\/v2\/media\/3141"}],"wp:attachment":[{"href":"https:\/\/redcon1online.com\/wp-json\/wp\/v2\/media?parent=3133"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/redcon1online.com\/wp-json\/wp\/v2\/categories?post=3133"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/redcon1online.com\/wp-json\/wp\/v2\/tags?post=3133"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}